IVF and Genetic Testing: Understanding PGD and PGS

Fertility problems can be very stressful, and IVF is the most common way of getting and having a child for many couples. Nevertheless, ensuring the baby is healthy is just as important as getting the mother pregnant. Today's reproductive medicine has available tools such as genetic testing & IVF, which allow the selection of embryos by embryologists and fertility experts through screening for genetic and chromosomal differences patterns.

 

This post will cover in detail the comparison between PGD and PGS, their advantages, and most importantly, the role of the best fertility center in Delhi in making your IVF journey a little less cumbersome.

 

What is Genetic Testing in IVF?  

 

Genetic testing in IVF refers to the examination of embryos obtained from IVF for genetic disorders or chromosomal abnormalities before their implantation. This procedure is considered very useful for couples who have:  

 

  • A history of genetic diseases in their family  
  • Repeated miscarriages or failures in IVF  
  • Mother’s age is 35 years or above  
  • Worries about chromosomal abnormalities  

Genetic testing detects problems at an early stage and also lessens the emotional and physical stress that is usually associated with several IVF tries.  

 

How Genetic Testing Works:

1. Embryo Biopsy: From every embryo, some cells are taken off with utmost care.

2. Laboratory Analysis: The cells are subjected to testing for genetic conditions or chromosomal abnormalities.

3. Embryo Selection: The transfer of the healthy embryos is done as the most probable one for the carrying to bring the baby.

Understanding PGD: Preimplantation Genetic Diagnosis  

 

PGD is a variety of genetic testing carried out to find particular inherited genetic defects in embryos. It is mainly designed for couples who might pass on conditions such as cystic fibrosis, sickle cell anemia, Tay-Sachs disease, or other recognized genetic diseases.  

 

Why PGD is Important

  • Couples with diagnosed genetic disorders can stop the disorder from being inherited by their offspring. 
  • It offers relaxation with the guarantee of disease-free embryos.  
  • It cuts the chance of psychological and physical pressure related to miscarriage or health problems to the ground.

Understanding PGS: Preimplantation Genetic Screening  

 

PGS is different from PGD in that it screens embryos for overall chromosomal health rather than specific genetic disorders. The goal of PGS is to identify embryos with the correct number of chromosomes, which reduces the risk of miscarriage and IVF failure.  

 

Who Can Benefit from PGS:

  • Women above 35 years of age, as chromosomal abnormalities increase with age  
  • Couples with repeated IVF failures or miscarriages  
  • Individuals concerned about embryo quality for implantation  

Advantages of PGS:

  • Increased implantations because of choosing normal embryos based on chromosomes  
  • Decrease in the number of miscarriages  
  • More chances of getting pregnant in one or two IVF treatments only 

PGD vs PGS: Key Differences

 

By the end of the 4th week, hCG levels are highly individualized, but the most important thing is that hCG levels are increasing steadily.

 

Normal hCG levels are expected at the 4th week to range from 5 to 426 mIU/mL. A steady increase every 48 to 72 hours is confirmation that low numbers are a completely normal condition. A healthy pregnancy is characterized by an unbroken increase, and this increase forms the basis of the doctor's assessment rather than a single reading.

 

At 4 weeks, abnormal hCG levels reveal patterns that can be categorized as either very low hCG numbers that do not rise properly, falling hCG levels, or surprisingly high hCG levels that do not correspond with the pregnancy stage. These patterns may point to issues such as an early pregnancy loss, ectopic pregnancy, or a miscalculated gestational age, but only the combination of continuous monitoring and ultrasound can ever reveal the actual reason.

 

What Sets SCI IVF Apart:

 

Advanced Laboratory: Furnished with the latest technology for embryo biopsy and genetic testing 

 

Expert Fertility Specialists: Certified professionals with vast knowledge in reproductive medicine 

 

High Success Rates: Tailored IVF and genetic testing strategies to boost results  

 

Compassionate Care: Help and encouragement during the whole IVF process  

 

Selecting SCI IVF means couples not only get the best IVF treatment in Delhi but also use the contemporary genetic screening techniques that increase the chance of a successful and healthy pregnancy.

 

How Genetic Testing Enhances IVF Success  

 

The inclusion of PGD or PGS in IVF therapy opens up different advantages:  

 

1. More Successful Implantation: Implantation of genetically healthy embryos occurs more frequently.    

 

2. Decreases the Risk of Miscarriage: The chromosomally abnormal embryos that are a primary contributor to miscarriage are avoided through PGS.

 

3. Ensures Healthy Offspring: PGD will protect the baby from the genetic disorders that have already been diagnosed.  

 

4. Minimizes Emotional and Financial Stress: Fertility patients might be able to skip over IVF cycles if they only use the embryos with the highest success rate.

Conclusion

Genetic testing and IVF are fundamental elements of contemporary reproductive medicine, providing an opportunity for couples to have a pregnancy that is healthier and more likely to succeed. The process with the use of PGD to help avoid having genetic diseases and PGS for sure selecting embryos with healthy chromosomes is one of the ways to help increase the chances of being successful when doing the IVF process.

At SCI IVF in Delhi, we provide the best and most compassionate Services and modern technologies to assurance the most successful IVF treatment. With the use of PGD and PGS, you can have a better chance of doing IVF successfully and having a healthy pregnancy, so you can walk confidently into parenthood.